Health care workers rolled up their sleeves for Pfizer's COVID-19 shot, marking the start of the biggest vaccination campaign in American history. If a second vaccine is authorized soon, as expected, 20 million people could be immunized by month’s end.
Here's a look at the vaccine, how it will be distributed, and what Americans think about it and the program.

Dr. Michelle Chester draws the Pfizer-BioNTech COVID-19 vaccine into a syringe at Long Island Jewish Medical Center, Monday, Dec. 14, 2020, in the Queens borough of New York. (AP Photo/Mark Lennihan, Pool)

Dr. Michelle Chester holds a syringe of the Pfizer-BioNTech COVID-19 vaccine at Long Island Jewish Medical Center, Monday, Dec. 14, 2020, in the Queens borough of New York. (AP Photo/Mark Lennihan, Pool)

Dr. Michelle Chester holds a vial of the Pfizer-BioNTech COVID-19 vaccine at Long Island Jewish Medical Center, Monday, Dec. 14, 2020, in the Queens borough of New York. (AP Photo/Mark Lennihan, Pool)

Sandra Lindsay, left, a nurse at Long Island Jewish Medical Center, is inoculated with the Pfizer-BioNTech COVID-19 vaccine by Dr. Michelle Chester, Monday, Dec. 14, 2020, in the Queens borough of New York. (AP Photo/Mark Lennihan, Pool)

Sandra Lindsay, left, a nurse at Long Island Jewish Medical Center, is inoculated with the Pfizer-BioNTech COVID-19 vaccine by Dr. Michelle Chester, Monday, Dec. 14, 2020, in the Queens borough of New York. (AP Photo/Mark Lennihan, Pool)

Dr. Michelle Chester holds a vial of the Pfizer-BioNTech COVID-19 vaccine at Long Island Jewish Medical Center, Monday, Dec. 14, 2020, in the Queens borough of New York. (AP Photo/Mark Lennihan, Pool)

Nurse Annabelle Jimenez, left, congratulates nurse Sandra Lindsay after she was inoculated with the Pfizer-BioNTech COVID-19 vaccine, Monday, Dec. 14, 2020, at the Jewish Medical Center, in the Queens borough of New York. (AP Photo/Mark Lennihan, Pool)

Nurse Sandra Lindsay, center, gives an interview after she was inoculated with the Pfizer- BioNTech COVID-19 vaccine, Monday, Dec. 14, 2020, at the Jewish Medical Center, in the Queens borough of New York. (AP Photo/Mark Lennihan, Pool)

Gov. Andrew Cuomo participates in a video conference call after a nurse was inoculated with the Pfizer-BioNTech COVID-19 vaccine, Monday, Dec. 14, 2020, at the Long Island Jewish Medical Center, in the Queens borough of New York. (AP Photo/Mark Lennihan)

Nurse Sandra Lindsay bumps elbows with hospital publicist Joseph Kemp after she was inoculated with the Pfizer-BioNTech COVID-19 vaccine, Monday, Dec. 14, 2020, at the Long Island Jewish Medical Center, in the Queens borough of New York. (AP Photo/Mark Lennihan, Pool)

Nurse Sandra Lindsay participates in a conference call with Gov. Andrew Cuomo after she was inoculated with the Pfizer-BioNTech COVID-19 vaccine, Monday, Dec. 14, 2020, at the Jewish Medical Center, in the Queens borough of New York. (AP Photo/Mark Lennihan, Pool)

Dr. Michelle Chester, left, holds a vial of the Pfizer-BioNTech COVID-19 vaccine after it was handed to her by pharmacy director Dana Rucco at Long Island Jewish Medical Center, Monday, Dec. 14, 2020, in the Queens borough of New York. (AP Photo/Mark Lennihan, Pool)

Pharmacy director Dana Rucco, center, shows medical director Richard Schwarz the container used to deliver the Pfizer-BioNTech COVID-19 vaccine, Monday, Dec. 14, 2020, at the Jewish Medical Center, in the Queens borough of New York. (AP Photo/Mark Lennihan, Pool)

Pharmacists wheel a box containing the Pfizer-BioNTech COVID-19 vaccine to a freezer as it arrives at Rhode Island Hospital in Providence, R.I, Monday, Dec. 14, 2020. (AP Photo/David Goldman)

A FedEx driver delivers a box containing the Pfizer-BioNTech COVID-19 vaccine to Rhode Island Hospital in Providence, R.I., Monday, Dec. 14, 2020. (AP Photo/David Goldman)

A box containing the Pfizer-BioNTech COVID-19 vaccine is wheeled to a freezer as it arrives at Rhode Island Hospital in Providence, R.I., Monday, Dec. 14, 2020. (AP Photo/David Goldman)