NORMAN, Okla. --- Receiver Ryan Broyles ... out for the season with a knee injury.
Running back Dominique Whaley ... out for the season with a broken ankle.
At least two of 12th-ranked Oklahoma's most dangerous offensive weapons won't be on the field Saturday when Iowa State visits Memorial Stadium at 11 a.m., but the Cyclones are hardly breathing a sigh of relief.
"They are not without other weapons," ISU head coach Paul Rhoads said. "Certainly, Landry Jones is a very gifted quarterback and has a number of receivers he can throw to, as I saw Saturday night as I watched their football game, and their running attack is equally as potent as it was before.
"The great demoralizer with all the talent is with the speed they run it."
Iowa State (6-4 overall, 3-4 Big 12) has tried mightily to forget its trip to Norman last season when the Sooners (8-2, 5-2) literally ran up and down the field on the Cyclones, racking up 383 yards and 31 points in the first half en route to a 52-0 win.
"We really felt the effects of that last year," Rhoads said of OU's up-tempo offense. "I think we have a better apprecation for that and have prepared for that better, and that showed in the Texas Tech game.
"We prepared hard for this game a year ago and did not answer (the bell) and embarrassed ourselves at times by not being ready to play at the snap. And we understand that as we go into (this week's) practices we have to be prepared for it this Saturday."
Junior linebacker A.J. Klein said it's the same story, different opponent for the Cyclones this week.
Since opening Big 12 play on Oct. 1 against Texas, ISU has faced a half-dozen of the top 15-rated offenses in the country from Baylor to Texas A&M to Texas Tech to Oklahoma State last Friday.
The Sooners, led by Jones, who has completed 65.3 percent of his passes for 3,796 yards and 28 touchdowns this season, rank fourth nationally with an average of 551.8 yards per game and sixth at 44.7 points per game.
"This is Oklahoma ... this is Landry Jones ... Kenny Stills is another great wide receiver," Klein said. "It's another complete opponent that we have to defend against."
The Cyclones will also be defending against two other factors - an angry Sooner squad coming off a stunning 45-38 loss to Baylor and the danger of its own complacency after becoming bowl -eligible with its upset win over Oklahoma State.
"I know Coach Stoops (Oklahoma's Bob), and he don't play," safety Ter'Ran Benton said. "He's mad.
"They're going to practice hard this week. They're going to come out banging and it's going to be a physical game. We've got to be ready for them."
ISU doesn't need a lot of added motivation.
"They really gave it to us good last year and we are going to have to make sure that doesn't happen again this year," quarterback Jared Barnett said.
As far as living in the past, the Cyclones have already put the Oklahoma State win to bed.
"Knowing that we have another great opponent ahead of us is a big thing," Klein said. "We played a great football game and we had great preparation going into it, and without great preparation it won't happen again.
"We want to keep this thing going. We want to build on it. (Being bowl-eligible) doesn't mean we want to go 6-6. How about 8-4 and really expanding on it ... take that next step with this program?"
So what needs to happen for Iowa State to stretch its current win streak to four Saturday on top of playing another outstanding game?
Rhoads said it's the same list as last week against Oklahoma State.
"They have a lot more talent than we do, there is no question about that," Rhoads said. "So there has to be an equalizer in there somehow with dropped balls or slipping on the turf or missed tackles that leads to a big play for us.
"Those type of things will still have to happen. Some you help create as a football team and some just work out that way on any given Saturday."
Iowa State (6-4, 3-4) at
No. 12 Oklahoma (8-2, 5-2)
When: 11 a.m. Saturday
Where: Norman, Okla.
Radio: KCNZ (1650 AM)
Line: Oklahoma by 28